Managers lack clear guidance on how to deal with a global disruption such as the current COVID-19 pandemic. This article reports on the results of an analysis of the effects of the Chinese government quarantines on companies and workers. The outcomes of this research offer important lessons for managers. In this study, among others, the authors cover the pandemic’s impact on China’s economy, global trade, production, and pollution. They also identify best practices, ranging from remote working, operational shocks, and the role of an organization in the wider community.